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Harvard study shows meditation immediately alters gene expression
Posted June 14, 2013 in Meditation & Yoga
Scientists from Harvard Medical School show that meditation, yoga and prayer elicit a physiological response that produces immediate positive changes in gene expression. The study, published in PLOS ONE last month, combined advanced expression profiling and systems biology analysis to both identify genes affected by these practices and to determine the potential biological relevance of those changes. Findings show both short and long-term practitioners upregulate genes associated with energy metabolism, mitochondrial function, insulin secretion and telomere maintenance while downregulating genes linked to inflammatory response and stress-related pathways. Top focus hubs identified include: mitochondrial ATP synthase, insulin and NF-κB pathway genes.
Authors conclude, “Our results for the first time indicate that [meditation] may evoke its downstream health benefits by improving mitochondrial energy production and utilization and thus promoting mitochondrial resiliency through upregulation of ATPase and insulin function. Mitochondrial resiliency might also be promoted by [meditation]-induced downregulation of NF-κB-associated upstream and downstream targets that mitigates stress.”